Defending champ Garbine Muguruza to take on homegirl Kristina Mladenovic in Paris

While giving her post-match speech, Mladenovic broke down in tears as the crowd chanted her nickname, "Kiki!"

Muguruza, who was seeded No. 4 in Paris, beat Serena Williams in the French Open final a year ago.

"I obviously was a little bit nervous", Muguruza said.

"Yeah, tough draw, but I think it's also tough for her". This will be their first meeting on clay court.Considering how "wide open" this French Open women's draw was supposed to be, there are an very bad lot of familiar names left in the brackets as we close the first week. I love this tournament no matter what happens. "I think she speaks like 25 languages, I heard", said Muguruza. I think that's the word I'm going to use, because I still don't know how I won that match.

"I experienced something in Germany where it was way more fired up, but I didn't criticise the crowd being unfair or anything, because it's also normal to see the crowd picking out their favourite". "That was a big thing on the match, but she managed to recover all those points", Muguruza said. "So I came back and played a more versatile game".

"My hand's been sore for about three or four days, since the day I played doubles here", Stosur told AAP.

Wozniacki missed the 2016 French Open because of an ankle injury.

The fourth-seeded Muguruza fell to No. 13 Kristina Mladenovic of France, 6-1, 3-6, 6-3, amid a noisy cauldron of partisan support at the Suzanne Lenglen show court.

It was the second year running that Williams lost to the Swiss in the Roland Garros fourth round.

Jelena Ostapenko, Mladenovich, Timea Bacsinszky, Elina Svitolina, Carlos Suarez Navarro, Petra Martic, Caroline Garcia, Alize Cornet, Veronica Cepede-Royg and Karolina Pliskova are yet to contest a major final.

Eighth-seeded Svetlana Kuznetsova of Russian Federation also moved on with a 7-6 (5), 4-6, 7-5 victory over 32nd-seeded Zhang Shuai.

Rain forced organizers to cancel or interrupt several matches on Saturday, including the all-French third round clash between Gael Monfils and Richard Gasquet and Kei Nishikori's tricky tie against South Korea's Chung Hyeon.

In addition, all eight women who play in the fourth round Monday are seeking a first major title, so it will be the first French Open since 1977 - and first major tournament anywhere since the 1979 Australian Open - without a past major champion among the quarterfinalists.

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